Importantly, these receptors were being discovered to have already been activated by a wide array of endogenous opioids in a concentration much like that observed for activation and signaling of classical opiate receptors. In turn, these receptors had been identified to get scavenging activity, binding to and decreasing endogenous amounts of opiate
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Importantly, these receptors were discovered to are actually activated by a wide array of endogenous opioids at a focus just like that observed for activation and signaling of classical opiate receptors. Subsequently, these receptors were found to have scavenging action, binding to and reducing endogenous levels of opiates accessible for binding to